Florence, capital of Italy’s Tuscany region and birthplace of the Renaissance, is home to masterpieces of art and architecture. One of its most iconic sites is the Florence Cathedral, with its terra-cotta-tiled dome engineered by Brunelleschi and bell tower designed by Giotto. The Galleria dell'Accademia displays Michelangelo’s “David,” while the Uffizi Gallery exhibits preeminent works such as Botticelli’s “The Birth of Venus” and da Vinci’s “Annunciation.” It is the most populous city in Tuscany, with approximately 381,000 inhabitants, expanding to over 1,510,000 in the metropolitan area. The Historic Centre of Florence attracts millions of tourists each year. Florence is believed to have the greatest concentration of art (in proportion to its size) in the world. Thus, cultural tourism is particularly strong, with world-renowned museums such as the Uffizi selling over 1.6 million tickets a year. Florence has approximately 35,000 hotel beds and 13,000 other accommodation facilities.